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KMID : 0545120120220010100
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Journal of Microbiology and Biotechnology
2012 Volume.22 No. 1 p.100 ~ p.106
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Metabolite Profiling and Bioactivity of Rice Koji Fermented by Aspergillus Strains
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Kim Ah-Jin
Choi Jung-Nam
Kim Ji-Young
Kim Hyang-Yeon
Park Sait-Byul
Yeo Soo-Hwan
Choi Ji-Ho
Liu Kwang-Hyeon
Lee Choong-Hwan
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Abstract
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In this study, the metabolite profiles of three Aspergillus strains during rice koji fermentation were compared. In the partial least squares discriminant analysis-based gas chromatography-mass spectrometry data sets, the metabolite patterns of A. oryzae (KCCM 60345) were clearly distinguished from A. kawachii (KCCM 60552) and only marginal differences were observed for A. oryzae (KCCM 60551) fermentation. In the 2 days fermentation samples, the overall metabolite levels of A. oryzae (KCCM 60345) were similar to the A. oryzae (KCCM 60551) levels and lower than the A. kawachii (KCCM 60552) levels. In addition, we identified discriminators that were mainly contributing tyrosinase inhibition (kojic acid) and antioxidant activities (pyranonigrin A) in A. oryzae (KCCM 60345) and A. kawachii (KCCM 60552) inoculated rice koji, respectively. In this study, we demonstrated that the optimal inoculant Aspergillus strains and fermentation time for functional rice koji could be determined through a metabolomics approach with bioactivity correlations.
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KEYWORD
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Rice koji, metabolite profiling, Aspergillus, gas chromatography-mass spectrometry, tyrosinase inhibition activity, antioxidant activity
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